Hemodynamic differences between black patients and white patients with essential hypertension. State of the art lecture.

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Hemodynamic differences between black patients and white patients with essential hypertension. State of the art lecture.

Physiological studies reported from our laboratory over the past several years have been reviewed and support epidemiological reports indicating that hypertensive cardiac and vascular disease runs a more severe course in the black patient. Although comparison of systemic hemodynamics failed to demonstrate that, for any level of arterial pressure, the magnitude of total peripheral resistance (wh...

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Differences in blacks and whites with essential hypertension: biochemistry and endocrine. State of the art lecture.

Overall, there is agreement that the origins of hypertension have a genetic basis. The genetic factors interact with environmental factors that influence expression and intensity of the disorder. As summarized in Table 1, there is evidence from the literature to identify pathways for the development of hypertension in blacks. Organ pathology, characteristic of the clinical phenotypic hypertensi...

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Night blood pressure responses to atenolol and hydrochlorothiazide in black and white patients with essential hypertension.

BACKGROUND Night blood pressure (BP) predicts patient outcomes. Variables associated with night BP response to antihypertensive agents have not been fully evaluated in essential hypertension. METHODS We sought to measure night BP responses to hydrochlorothiazide (HCTZ), atenolol (ATEN), and combined therapy using ambulatory blood pressure (ABP) monitoring in 204 black and 281 white essential ...

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ژورنال

عنوان ژورنال: Hypertension

سال: 1990

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.15.6.675